WebTeclistamab, sold under the brand name Tecvayli, is a human bispecific monoclonal antibody used for the treatment of relapsed and refractory multiple myeloma. It is a … WebMar 23, 2024 · Teclistamab is used to treat adults with multiple myeloma who have received at least 4 treatment regimens and their cancer has returned or did not respond …
Updates on Phase 1b TRIMM-2 Study Results of Teclistamab Plus ...
WebOct 25, 2024 · Teclistamab is a type of drug called a bispecific antibody. It targets a protein on myeloma cells called BCMA, as well as a protein on the immune system’s T cells called CD3. Teclistamab forces the T cells to recognize the multiple myeloma cells and attack them. BCMA has emerged as a promising target for multiple myeloma drugs. WebDailyMed is a website operated by the U.S. National Library of Medicine (NLM) to publish up-to-date and accurate drug labels (also called a "package insert") to health care … bitchily
Teclistamab Memorial Sloan Kettering Cancer Center
WebJun 15, 2024 · Daratumumab (Dara) is a CD38-targeting monoclonal antibody with direct on-tumor and immunomodulatory mechanisms of action. The preliminary results from the phase 1b multicohort TRIMM-2 study showed tolerable safety with no overlapping toxicities, and encouraging efficacy, supporting the combination of teclistamab with daratumumab for … WebMar 23, 2024 · Teclistamab side effects. Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.. Tell your medical caregivers if you have signs of cytokine release syndrome (CRS), a serious side effect: fever, chills, trouble breathing, confusion, severe vomiting or … WebSep 22, 2024 · Teclistamab also depleted BCMA+ cells in bone marrow samples from MM patients in an ex vivo assay with an average EC50 value of 1.7 nM. Under more … darwin phone number