Irisin a fascinating field in our times
WebIrisin, a fascinating field in our times Irisin is a muscle-secreted hormone that is generated by cleavage of membrane protein FNDC-5 (fibronectin type III domain-containing protein 5). Irisin is considered to be a mediator of exercise-induced metabolic improvements, such as browning of white adipose tissue, and is known to alleviate several ...
Irisin a fascinating field in our times
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WebFurthermore, our findings reveal that irisin boosts the transcriptional expression of PPAR-γ and Nrf2 in a STAT6-dependent manner. ... Irisin, a fascinating field in our times[J] Trends Endocrinol. Metabol., 33 (9) (2024), pp. 601-613. View PDF View article View in Scopus Google Scholar [25] WebJan 25, 2024 · Irisin was discovered in 2012 as a potential myokine, cleaved from its parent FNDC5 in response to exercise, and inducing browning of white adipose tissue (WAT) Hundreds of studies reported irisin levels in response to different physiological challenges but are compromised by flawed quantitative assays
WebSep 21, 2024 · The work published by Chi et al. 6 further supports the view of FNDC5/irisin-enriched EVs as critical rejuvenating agents through long-distance communication between hormone-producing cells and cells that express hormone receptors, beyond the well-known role as autocrine and paracrine mediators. 14 Indeed, the additional proof-of-concept ... WebJul 21, 2024 · Irisin is considered to be a mediator of exercise-induced metabolic improvements, such as browning of white adipose tissue, and is known to alleviate …
WebOct 27, 2024 · In his lab, I focused on the role of the newly discovered exercise hormone FNDC5 and its secreted form irisin. I identified a novel PGC1a–FNDC5–BDNF pathway in the hippocampus that is induced by... WebIsa Arsén is a certified bleeding heart based in South Texas, where she lives with her spouse and a comically small dog. Her work has been featured in publications including Stone of …
WebFeb 8, 2024 · Over the past decade, it has become clear that irisin is a molecular mimic of exercise and shows various beneficial effects, such as browning of adipocytes, modulation of metabolic processes, regulation of bone metabolism, and …
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