WebJan 27, 2010 · Abstract The quakingviable mouse ( qkv) is a spontaneous recessive mouse mutant with a deletion of ∼1.1 Mb in the proximal region of chromosome 17. The deletion affects the expression of three genes; quaking ( Qk ), Parkin-coregulated gene ( Pacrg) and parkin ( Park2 ). WebOct 1, 1999 · Although the quaking alleles can be grouped based on embryo lethality or viable dysmyelination, each allele deviates in some significant way from these general phenotypes to make it a unique and valuable resource for fine-structure/function studies and modeling human neural tube defects, as well as seizure and myelination disorders ( Table …
Mice, Quaking Profiles RNS
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Reproductive and neurological Quaking viable phenotypes in a …
WebJul 25, 2016 · Mouse anti-adenomatous polyposis coli (CC1) binds Quaking. (a) On western blots of protein lysate from cultured rat mature oligodendrocytes (7 DIV), the CC1 antibody detects an ~ 40 kDa band that is not present in cultured rat cortical neuron protein lysate. GAPDH was used as a loading control. WebPreble’s jumping mouse is a true hibernator, usually entering hibernation in September or October and emerging the following May, after a long hibernation period of seven to eight … WebThe “Quaking” mouse is a recessive autosomal mutant characterized by a deficient myelination of the central nervous system. The disease is recognized at about the twelfth … gonzaga basketball free live streaming today